CONGENITAL MALFORMATIONS:
DEFINED:As structural malformations of prenatal onset.
1.Those that represent a single primary gene defect
2.Those that represent a multiple malforamation syndrome.
SINGLE PRIMARY DEFECTS IN DEVELOPMENT:
MALFORMATION: A primary structural defect arising from a localized error in morphogenesis.
DEFORMATION: An alteration in shape / structure of a part that has differentiated normally.
DISRUPTION: Structural defect resulting from
destruction of a previously normally formed part.
DYSPEPSIA: Refers to an abnormal organization of cells And the structural Consequences.
6 MOST COMMON single primary defects in development
1. Congenital hip dislocation
2. Talipes Equinovarus
3. cleft lip
4. Cardiac septal defects
5. cleft palate
6. Defects in neural tuve closure
