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22.7.09

MECHANISMS OF SEIZURES

  • The precis mehanism is unknown.
  • Several physiological facotrs.
  • Group of neurons generating signigicant bust dicharge.
  • impairment of GABAergic inhibitory Systerm.
  • Excitatory Glutamatergic synapses & Amino -acids.
  • Areas of neuronald death,reorgainzation after injury.
  • Kindling.
  • Age Specific -- ? undederdeve loped brain.
  • Functional immaturinty of substantia nigra.
  • Genetic Factors

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